Itinai.com an advertising light picture for medical analysis 5c395afe 218e 4906 a405 4791096c0e54 3
Itinai.com an advertising light picture for medical analysis 5c395afe 218e 4906 a405 4791096c0e54 3

Study protocol of short versus long-term levetiracetam in brain tumors (LIBRA): a phase 3 randomized controlled trial

Background

Seizures are common in patients with brain tumors, affecting their daily lives and increasing healthcare costs. Levetiracetam is the most frequently prescribed medication to prevent seizures after brain surgery. Typically, patients take it for 2-3 years, but the actual need for such a long duration is unclear. This study aims to compare a shorter use of levetiracetam with the standard longer use to see if both are equally effective.

Methods

Adults over 18 years old, who have had surgery for a primary brain tumor and have experienced seizures, will be included in the study. Patients will be randomly assigned to either continue taking levetiracetam for an additional 2 years or to stop taking it after tapering off. The main goal is to see how many patients remain seizure-free for 2 years. Other goals include assessing the impact of seizures on quality of life and overall survival.

Discussion

This trial will provide important evidence about how long patients with brain tumors should take anti-seizure medication. If a shorter duration is found to be just as effective, it could lead to less medication use, reduced side effects, and improved quality of life for patients.

Ethics and Registration

The study has received ethical approval and is registered with clinical trial databases.

Opportunities Based on Trial Data

By analyzing the results of this trial, healthcare providers can identify ways to improve treatment protocols for brain tumor patients, focusing on measurable outcomes like seizure control and quality of life.

Goals for Clinics and Patients

Clear goals will be set based on the trial’s findings to enhance patient care and treatment strategies in clinical settings.

AI Tools for Clinical Needs

AI solutions can be tailored to meet specific clinical tasks, helping to analyze data and improve patient management.

Implementation Steps

Start with a pilot project to track results using AI solutions, ensuring that the findings from this trial are effectively translated into real-world practices.

Contact Us for AI Solutions in Medical Management

For more information, reach out to us on:

AI-Powered Health Tools

Interactive AI Tools to Help You Understand Your Health

Solutions for Smart Healthcare

Clinical Research