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The Effect of Curcumin on Reducing Atherogenic Risks in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial

The Effect of Curcumin on Reducing Atherogenic Risks in Obese Patients with Type 2 Diabetes: A Randomized Controlled Trial

Study Overview

Curcumin, derived from turmeric root, has been found to have anti-inflammatory effects, and this study aimed to assess its potential in reducing the risk of atherosclerosis in obese patients with type 2 diabetes. The trial, involving 227 participants, utilized a randomized, double-blind, placebo-controlled design to evaluate the impact of curcumin over a 12-month period.

Key Findings

After 12 months, participants receiving curcumin demonstrated a significant reduction in pulse wave velocity (p < 0.001) and saw decreased levels of cardiometabolic risk biomarkers, including low-density lipoprotein cholesterol and small dense low-density lipoprotein cholesterol, all with p values less than 0.001. Additionally, markers of inflammation, such as high-sensitivity C-reactive protein, interleukin-1 beta, interleukin-6, and tumor necrosis factor-alpha, were significantly lower in the curcumin group (p values < 0.001).

The study concluded that curcumin intervention was associated with a reduction in pulse wave velocity and an improvement in cardiometabolic risk profiles, suggesting that curcumin treatment may effectively reduce atherogenic risks in type 2 diabetes patients with obesity.

Value in Healthcare

Clinical trials play a crucial role in developing safe and effective treatments, and it’s essential to translate their benefits into everyday medical practice. Utilizing AI-driven platforms, such as DocSym, can help consolidate standards, protocols, and research into an easily accessible knowledge base for clinicians, streamlining operations and enhancing patient care. Additionally, mobile apps can support scheduling, treatment monitoring, and telemedicine, contributing to improved patient outcomes and digital expansion of services.

AI integration in clinics can enhance workflows, improve patient outcomes, and reduce paper-based routines, ultimately advancing healthcare delivery. Learn more about how AI can support medical practices at aidevmd.com.

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