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THE EFFECT OF LOW MOLECULAR WEIGHT HEPARIN SODIUM IN THE TREATMENT OF ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE COMORBID WITH PULMONARY HEART DISEASE ON PROMOTING THE BALANCE OF BLOOD VESSELS

The Effect of Low Molecular Weight Heparin Sodium in Treating Acute COPD with Pulmonary Heart Disease

Overview

Chronic obstructive pulmonary disease (COPD) affects about 13.7% of people over 40 in China, with nearly 100 million individuals suffering from it. This study focuses on how Low Molecular Weight Heparin Sodium can help treat acute exacerbations of COPD, especially when combined with pulmonary heart disease (PHD).

Study Methods

We studied 92 patients with acute COPD and PHD from January 2019 to May 2021. They were divided into two groups:

  • Control Group: Received basic treatment.
  • Observation Group: Received basic treatment plus Low Molecular Weight Heparin Sodium.

We monitored changes in blood gas levels, blood flow properties, heart function, and serum factors to evaluate effectiveness and safety.

Key Findings

  • Higher Effectiveness: The observation group had a 95.65% effective rate, compared to 82.61% in the control group.
  • Improved Health Metrics: Key health indicators like left ventricular ejection fraction (LVEF), walking distance, and oxygen levels improved significantly in the observation group.
  • Reduced Inflammation: Levels of harmful substances decreased, indicating less inflammation.
  • Safety: No significant difference in adverse effects between the two groups.

Conclusion

Low Molecular Weight Heparin Sodium can effectively reduce inflammation and improve blood flow, leading to better treatment outcomes for patients with acute COPD and PHD.

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