Efficacy and Safety of Methotrexate Plus Hydroxychloroquine Combination Therapy vs. Methotrexate Monotherapy in the Treatment of Rheumatoid Arthritis: A Randomized Controlled Clinical Trial
Key Findings:
Combining methotrexate (MTX) with hydroxychloroquine (HCQ) showed a more significant reduction in pain, disease activity, and inflammatory factors compared to MTX monotherapy.
The quality of life was also higher in the MTX + HCQ group.
Both treatment options demonstrated improvements in symptoms and quality of life for rheumatoid arthritis patients.
The combination therapy outperformed MTX monotherapy across all measures, indicating its potential as the preferred initial treatment for rheumatoid arthritis.
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