Performance and acceptability of self-collected specimens for diagnosis of rectal and pharyngeal Chlamydia trachomatis and Neisseria gonorrhoeae infections among men who have sex with men in China: a randomized controlled trial

Self-Collection of Specimens for Chlamydia and Gonorrhea Testing

Study Overview

This study focused on whether self-collected samples could effectively diagnose Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infections among men who have sex with men (MSM) in China. The goal was to make testing more accessible for those who hesitate to visit clinics.

Key Findings

  • Prevalence Rates: Out of 325 participants, 13.6% had rectal CT, 5.2% had rectal NG, 1.5% had pharyngeal CT, and 2.8% had pharyngeal NG.
  • Accuracy: Self-collected rectal samples showed a 98.8% agreement for CT and 99.4% for NG when compared to clinician-taken samples. Pharyngeal samples showed a 99.4% agreement for CT and 98.2% for NG.
  • Sensitivity and Specificity: Self-collected samples had high sensitivity and specificity rates, making them reliable for testing.
  • Acceptability: 62% of MSM preferred self-sampling, and 90.2% were willing to use it again.

Practical Solutions and Value

Implementing self-collection for CT and NG testing can:

  • Improve accessibility for MSM.
  • Provide reliable test results.
  • Increase comfort and preference among patients.

Recommendation

It is recommended that healthcare providers offer self-collection options as part of STI screening services for MSM.

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