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Itinai.com a close up shot of a scientist wearing a pristine db6a7c73 f520 44e3 bb74 10eabe38d600 1

A Virtual Breakthrough Series Collaborative for Missed Test Results: A Stepped-Wedge Cluster-Randomized Clinical Trial

A Virtual Breakthrough Series for Missed Test Results

Importance

Missed test results happen when healthcare providers do not follow up on test outcomes in a timely manner, causing delays in diagnosis and treatment.

Objective

This study aimed to assess how a quality improvement program, called the Virtual Breakthrough Series (VBTS), impacts the follow-up rates of two critical test results: chest imaging for lung cancer and lab results for colorectal cancer.

Study Overview

This clinical trial took place from February 2020 to March 2022 across 12 Department of Veterans Affairs (VA) medical centers. It involved three phases: preintervention, action, and continuous improvement. Teams included a project leader and various experts from different fields. Data analysis occurred from April 2022 to March 2024.

Intervention

All teams engaged in the VBTS, which provided training on how to reduce missed test results in their facilities.

Main Outcomes

The primary goal was to measure changes in the follow-up rates of abnormal test results between the preintervention and action phases. Secondary goals included evaluating the intervention’s effects across different cohorts and sites.

Results

Eleven teams completed the VBTS, implementing 47 unique strategies to address missed test results. In total, 40,027 colorectal cancer tests were conducted, revealing 5,130 abnormal results, with 1,286 flagged as missed. For lung cancer, 376,765 tests were done, with 7,314 abnormal results, and 2,436 flagged as missed. Overall, there was no significant change in follow-up rates across all study phases. However, one site with the lowest follow-up rate improved from 27.8% to 55.6% after the intervention.

Conclusions

While the VBTS did not show a general improvement in follow-up rates, it proved beneficial for sites with previously low performance.

Trial Registration

ClinicalTrials.gov Identifier: NCT04166240.

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