Approaches for improvement of ocular surface condition in primary open-angle glaucoma

Improving Eye Health in Glaucoma Patients

Study Overview

This study looks at how to improve eye surface health in patients with primary open-angle glaucoma (POAG) who also have dry eye syndrome (DES) and meibomian gland dysfunction (MGD).

What We Did

We included 48 patients with stage II POAG, who were treated with a specific eye drop combination that contains benzalkonium chloride (BAC). Patients were divided into two groups:

Group 1: 24 patients received BAC-free eye drops along with eyelid hygiene products like Blepharogel cleansing, Blepharolotion, and Blepharogel-1.
Group 2: 24 patients received only BAC-free eye drops.

We measured their eye health at the start and after 4 weeks of treatment, looking at various indicators like the OSDI score, tear break-up time (TBUT), and MGD severity.

What We Found

After 4 weeks:

Group 1 showed significant improvements in OSDI, TBUT, and MGD severity.
Group 2 only showed improvements in OSDI and TBUT.

The results suggest that combining BAC-free eye drops with eyelid hygiene is more effective than using just BAC-free drops alone.

Conclusion

For patients with POAG, DES, and MGD, switching to BAC-free eye drops along with eyelid hygiene is a better approach for improving eye health.

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