Clinical trials

Understanding Cluster Headaches and New Research Findings Cluster headaches are severe headaches that occur in cycles, with periods of intense pain followed by times without symptoms. Recent research has explored how certain channels in our body, called KATP channels, might trigger these headaches. Study Overview In a study involving 41 participants, researchers looked at the […] ➡️➡️➡️

Background Knee injuries involving the patella are common. While exercise therapy is effective, challenges like appointment scheduling and limited sessions may hinder progress. Home-based exercise using digital health apps can overcome these issues. Study Objective This study evaluated a 12-week web-based exercise program to improve knee function and reduce pain in patients with patella disorders. […] ➡️➡️➡️

Objective The goal of this study was to evaluate how effective a comprehensive rehabilitation program is for patients with severe leg issues due to combat injuries and chronic critical lower limb ischemia (CCLLI). This program included treatments like stem cell therapy, acupuncture, physiotherapy, and physical exercises. Patients and Methods In a six-month clinical trial, 40 […] ➡️➡️➡️

Background Many women fear the pain of childbirth, which often leads them to choose cesarean delivery instead of natural childbirth. This study explores how chewing gum can help reduce anxiety and pain during labor. Study Overview This research was conducted in two public health centers in Babol, Iran, from May 2021 to October 2022. It […] ➡️➡️➡️

Background Acne is a common skin issue that many people face. There are various treatments available, but recent studies suggest that inflammation in the body may also play a role in acne. Some natural supplements, including plant-based products, may help address these underlying causes. However, there are not many well-conducted studies to confirm their safety […] ➡️➡️➡️

Overview of Caffeine’s Effects on Vertical Jump Performance This study investigates whether caffeine improves vertical jump performance in collegiate athletes, specifically those in NCAA Division II. While caffeine is often thought to enhance athletic performance, results have been mixed, particularly at levels allowed by collegiate sports. Study Details Forty NCAA Division II athletes (18 females […] ➡️➡️➡️

Background Cancer patients often feel anxious and uncertain when they need radiological imaging. This study looks at how a nurse-led educational program can help reduce this anxiety and improve understanding of the imaging process. Aims The goal of this study was to see if a nurse-led psychoeducational program could improve knowledge and reduce psychological distress […] ➡️➡️➡️

Background Expanding malaria community case management (mCCM) to all ages can improve access to healthcare in areas that need it the most. This study looked at how practical and cost-effective this change would be in the Farafangana district of Madagascar. Study Methods Researchers conducted a trial across 30 health centers involving 502 community health workers […] ➡️➡️➡️

Study Overview This study looked at how effective three different treatments are for patients with lateral epicondylitis (commonly known as tennis elbow). Treatment Groups Fifty-four patients were randomly divided into three groups: Epicondylitis bandaging Wrist dorsiflexion splinting Kinesio taping Patient Assessment Patients were evaluated using: Visual Analog Score (VAS) – for pain level Disabilities of […] ➡️➡️➡️

“`html Purpose This study aimed to compare the effectiveness of two methods for draining subretinal fluid during surgery for retinal detachment. Methods We looked at 43 patients with retinal detachment, dividing them into two groups: Group A: 22 patients received internal drainage using a special tool. Group B: 21 patients received external drainage during surgery. […] ➡️➡️➡️

Study Overview This study compared a new robotic-assisted navigation system with traditional methods for taking biopsies of tumors in the chest and abdomen. It involved 140 patients who needed this procedure. Results Success Rate: The robotic system successfully located the biopsy site 84.1% of the time, compared to just 43.7% for the traditional method. Adjustment […] ➡️➡️➡️

Background Recent studies show that blood tests can help diagnose and predict the progression of Alzheimer’s disease (AD), especially in its early stages. This research aimed to explore how these blood markers can forecast outcomes in patients with mild to moderate AD. Methods We analyzed data from a clinical trial called T2 Protect AD, which […] ➡️➡️➡️

“`html Background Oral mucositis (OM) is a painful condition that many children face when undergoing chemotherapy. This clinical trial tested two treatments: photobiomodulation (PBM) to prevent OM and photodynamic therapy (PDT) to treat it in children with blood cancers. Methods In the prevention phase, some patients did not receive PBM initially but were given it […] ➡️➡️➡️

Study Overview This study investigates how using a collagen sponge in the socket after removing impacted lower third molars affects pain, mouth opening, and the risk of dry socket (Alveolar Osteitis). Study Method Researchers conducted a randomized trial with patients who had teeth removed from both sides of their mouths. On one side, they applied […] ➡️➡️➡️

Objective This study aimed to see how well cariprazine helps reduce anxiety symptoms in adults diagnosed with major depressive disorder (MDD) who did not respond well to other antidepressants. Methods We looked at data from a large study with 751 participants. We focused on how cariprazine at doses of 1.5 mg and 3.0 mg per […] ➡️➡️➡️

Background and Objective Measuring breathlessness in early-stage lung cancer can be tricky because different scales may give varying results. This study looks at three common scales: the Modified Borg Scale (mBorg), the Numerical Rating Scale (NRS), and the Dyspnea-12 scale (D-12). The goal is to find out how these scales agree with each other and […] ➡️➡️➡️

Background American Indians face significant health challenges, particularly high rates of Type 2 diabetes (T2D). To address this issue, we launched a program called Together Overcoming Diabetes (TOD), which focuses on culturally relevant, home-based prevention strategies. Study Overview This study involves collaboration between five tribal nations and university researchers, starting in 2021. We are conducting […] ➡️➡️➡️

Background Excess fat in the liver can lead to a condition called metabolic dysfunction-associated steatotic liver disease (MASLD). This study looked at how weight loss affects fat buildup in the liver. Study Overview Overweight adults with either high or normal liver fat were given dietary counseling for 6 months. Researchers measured various factors to understand […] ➡️➡️➡️

Understanding Acute Pancreatitis Acute pancreatitis (AP) is a serious condition that needs quick diagnosis and treatment. Correctly assessing how severe the condition is helps in providing the right care at the start. Aim of the Study This study looks at how effective certain inflammatory markers and scoring systems are in determining the severity of early-phase […] ➡️➡️➡️

Overview of the Study Total knee arthroplasty (TKA) is important for relieving pain and enhancing life quality in patients with severe knee arthritis. However, many patients experience sleep problems after surgery, which can last for months and affect recovery. Robotic-Assisted TKA vs. Conventional TKA This study compared sleep quality in patients who underwent robotic-assisted TKA […] ➡️➡️➡️