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Comparative study of geometric localization technique and CT-guided percutaneous localization technique for peripheral GGO in wedge resection: a randomized controlled trial

Clinical Trial Overview

This study compares two methods for locating ground glass opacity (GGO) in the lungs during surgery: the Geometric Localization Technique (GLT) and the CT-guided Percutaneous Localization Technique (CPLT). The goal was to determine which method is more effective, safe, and accurate.

Study Details

A total of 455 patients diagnosed with pulmonary GGO were included in the trial. They were divided into two groups:

  • GLT Group: 228 patients used the GLT method.
  • CPLT Group: 227 patients used the CPLT method.

Results

The study found several key differences between the two methods:

  • Successful Localization Rate: GLT achieved 99.6% while CPLT achieved 94.3%.
  • Sufficient Resection Margin: GLT had a rate of 99.6% compared to CPLT’s 87.2%.
  • Complications: The GLT group had no complications, while 17.6% of patients in the CPLT group experienced localization-related issues.

Conclusions

GLT is at least as effective and accurate as CPLT, with a significant safety advantage. This suggests that GLT may be a better choice for patients undergoing wedge resection for GGO.

Opportunities for Improvement

Based on the trial data, clinics can set clear goals such as:

  • Increasing successful localization rates.
  • Reducing complications related to localization.

Implementation Steps

To enhance clinical outcomes, consider starting with a pilot project using AI tools that fit specific clinical needs. Monitor results to assess the real-world impact of using GLT.

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