Comparison of endoscopic versus focused parathyroidectomy in surgical management of single-gland primary hyperparathyroidism: a randomized clinical trial

Comparison of Endoscopic versus Focused Parathyroidectomy in Surgical Management of Single-Gland Primary Hyperparathyroidism: A Randomized Clinical Trial

Key Findings:

  • The success rate for endoscopic parathyroidectomy was 95.3% compared to 77.1% for focused parathyroidectomy within the first five minutes.
  • Postoperative calcium levels were significantly lower in the focused parathyroidectomy group.
  • The focused parathyroidectomy method had a significantly shorter operation time.
  • Patient satisfaction with cosmetic outcome was significantly higher in the endoscopic group.

Conclusion:

The endoscopic technique was found to be superior in managing single-gland primary hyperparathyroidism due to higher success rates, better postoperative calcium levels, shorter operation time, and improved cosmetic outcomes. Patient selection and accurate adenoma localization were highlighted as vital considerations in this method.

PMID: 38907761 | DOI: 10.1007/s00423-024-03390-0

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