Study Title: Demonstrating the effectiveness of intra-articular prolotherapy combined with peri-articular perineural injection in knee osteoarthritis: a randomized controlled trial
Summary
This study compared the effectiveness of different treatments for knee osteoarthritis (KOA). It involved 60 patients aged 48-80 with grade 2 or 3 KOA. Patients were divided into three groups and received different treatments. The study measured pain, joint function, and pressure pain threshold at 2, 4, and 8 weeks.
Results
After treatment, all groups showed improvement in pain, joint function, and pressure pain threshold. At 4 and 8 weeks, the combined treatment group showed significantly lower pain and better joint function compared to the other groups. The pressure pain threshold also improved significantly in the combined treatment group compared to the single treatment groups.
Conclusion
The study suggests that the combined treatment of intra-articular prolotherapy and peri-articular perineural injection is more effective in reducing pain and improving knee function in the short term. This combination could be considered by clinicians to improve symptoms in KOA patients.
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