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Effect of an herbal gel for the prevention of radiation dermatitis-related symptoms: an open-label randomized clinical trial

Study Overview

This study focused on radiation-induced dermatitis (RID), a common side effect of radiotherapy in cancer patients. The goal was to test an herbal gel to see if it could prevent RID and its symptoms.

Study Design

Cancer patients were divided into two groups:

  • Prophylactic Group: Received the herbal gel one day before starting radiotherapy.
  • Interventional Group: Received the herbal gel only after developing moderate RID symptoms.

The study measured skin symptoms, quality of life, and any side effects from the gel.

Results

Out of 71 participants:

  • The prophylactic group experienced significant relief from itching, pain, and burning sensations.
  • There was no significant difference in the overall occurrence of RID between the two groups.
  • The gel did not negatively impact the patients’ quality of life.
  • No adverse reactions to the gel were reported.

Conclusions

The herbal gel showed promise in reducing symptoms related to radiation dermatitis safely. It could be considered for use in patient care, especially for those undergoing treatment for breast, lung, and head and neck cancers.

Opportunities for Clinics and Patients

Based on the trial data, clinics can:

  • Set clear goals for using the herbal gel to manage RID symptoms.
  • Measure outcomes such as symptom relief and patient satisfaction.
  • Implement the gel in a step-by-step approach, starting with pilot projects to track effectiveness.

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