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Effect of Two Types of Time-Restricted Eating on Glycemic, Lipid Indices and Weight of Women with Polycystic Ovary Syndrome

Effect of Two Types of Time-Restricted Eating on Women with Polycystic Ovary Syndrome

Introduction

Polycystic ovary syndrome (PCOS) is a common hormone disorder affecting women of reproductive age. It increases the risk of various health issues like metabolic syndrome, heart disease, and type 2 diabetes. Time-restricted eating (TRE) is a form of intermittent fasting that may help with weight loss and improve blood sugar and fat levels. This study explores whether early TRE (eTRE) or middle TRE (mTRE) is more effective for women with PCOS.

Methods

In this 6-week clinical trial, we compared the effects of eTRE (8:00 AM – 6:00 PM) and mTRE (11:00 AM – 9:00 PM) on 50 overweight or obese women aged 18-40 with PCOS. We measured changes in body weight, waist circumference, body mass index (BMI), fasting blood sugar, fasting insulin, and cholesterol levels. We used statistical tests to assess the differences between the two groups.

Results

After 6 weeks, both groups showed significant improvements in body weight, waist circumference, BMI, blood sugar, and insulin resistance (p = 0.0001). However, eTRE led to notable improvements in fasting insulin, total cholesterol, and LDL cholesterol (p = 0.0001), while no significant changes were observed in the mTRE group. Changes in triglycerides and HDL were also not significant (p = 0.05).

Conclusion

Our study suggests that early TRE is more effective than middle TRE for weight loss and reducing insulin resistance in women with PCOS. However, the effects on cholesterol levels are unclear, indicating a need for more research.

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