Effects of Marrubium vulgare Extract on Hormonal Parameters and Clinical Findings in Polycystic Ovarian Syndrome
Introduction
Polycystic ovary syndrome (PCOS) is a common hormonal disorder in women of reproductive age. Marrubium vulgare has been traditionally used in Persian medicine to treat PCOS symptoms. This study investigates its effects on hormonal levels and symptoms of PCOS.
Methods
In this clinical trial, patients diagnosed with PCOS were randomly assigned to receive either Marrubium vulgare extract (250 mg daily) or a placebo for three months. We measured body mass index (BMI), hormone levels (testosterone, estradiol, progesterone), and other health indicators at the start and end of the study. We also assessed symptoms like acne and irregular menstrual cycles.
Results
In the placebo group, there were no significant changes in health indicators. However, in the group taking Marrubium vulgare:
- BMI, testosterone levels, and hirsutism scores significantly decreased.
- Symptoms like irregular menstruation and dysmenorrhea were notably reduced.
- The reductions in hirsutism, fasting blood sugar, and testosterone were greater compared to the placebo group.
Conclusion
The study suggests that Marrubium vulgare is a safe and effective treatment for PCOS.
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