Effects of Discontinuing Antihypertensive Treatment in Nursing Home Residents with Dementia
Key Findings
Discontinuing antihypertensive treatment in nursing home residents with dementia did not significantly reduce neuropsychiatric symptoms or improve quality of life compared to usual care.
Study Details
The study involved 205 participants with moderate-to-severe dementia and systolic blood pressure ≤160 mmHg. They were randomized to either discontinue antihypertensive treatment or receive usual care.
Results
At the 16-week follow-up, no significant differences were found between the two groups in terms of neuropsychiatric symptoms or quality of life. Serious adverse events occurred in 36% of the discontinuation group and 24% of the usual care group.
Conclusion
Based on the study findings, discontinuing antihypertensive treatment in older adults with dementia does not appear to be safe or beneficial enough to be recommended.
Value of Clinical Trials
Clinical trials are essential for developing safe and effective treatments. They provide valuable insights that can guide medical practice and improve patient care.
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