Experience with the use of undenatured type II collagen in patients with stage III knee osteoarthritis: a multicenter, prospective, double-blind, placebo-controlled, randomized trial

Introduction

Current treatments for osteoarthritis (OA) use a mix of medications and lifestyle changes. A natural supplement called undenatured chicken collagen type II (NK2) is safe and effective for joint health and can be used alone or with other OA treatments.

Aim of the Study

This study aimed to test how effective a product called Artneo, which contains NK2, is for patients with stage III knee OA compared to a placebo in a well-structured clinical trial.

Study Details

The study involved 212 patients from 12 locations in Russia, specifically focusing on 50 patients with stage III knee OA. Most participants were women aged between 44 to 75 years. Patients were randomly divided into two groups:

  • Group 1 (Artneo group): 28 patients took 1 capsule of Artneo daily for 180 days.
  • Group 2 (Placebo group): 22 patients took a placebo that looked the same as Artneo and followed the same schedule.

To measure the effectiveness, researchers looked at pain levels, joint function, quality of life, and the need for pain-relief medications.

Results

The trial found that Artneo significantly outperformed the placebo in reducing pain and stiffness, improving joint function, and enhancing overall quality of life. It also had a good safety record.

Conclusion

Artneo showed high effectiveness and safety for patients, especially those with stage III knee OA.

Opportunities for Clinics and Patients

Based on trial data:

  • Define Measurable Outcomes: Set clear goals for treatment success using NK2.
  • Select Appropriate AI Tools: Choose AI solutions that meet specific clinical needs.
  • Implement Gradually: Start with a pilot project to measure the impact of NK2 on patients.

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