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Incidental diagnosis of lung cancer on chest CT scan performed for suspected or documented COVID-19 infection

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Study Summary

Recent studies have found that chest CT scans can be beneficial for lung cancer screening. During the COVID-19 pandemic, many chest CT scans were performed on a large population. This study aimed to describe the incidence and characteristics of lung cancer detected on chest CT scans done for suspected or confirmed COVID-19 infection, outside of a clinical trial setting.

Key Findings

  • Over the study period, 24,390 patients had at least one chest CT scan.
  • 72 lung cancer diagnoses were made, with an incidence of 0.30%.
  • Median age of diagnosed patients was 67.4 years, with 50.0% being current smokers and 55.6% having adenocarcinoma.
  • Half of the lung cancer patients did not meet the National Lung Screening Trial inclusion criteria.
  • 36.1% of patients were diagnosed at an early stage, with 34.7% of them receiving radical curative treatment.
  • 26 patients died during the follow-up, but none were in early stages.
  • The median overall survival in lung cancer patients was 693 days.

Implications

A large-scale chest CT scan strategy for suspected or documented COVID-19 infection has allowed for a significant proportion of early-stage lung cancer diagnoses, all of which have benefited from curative treatment.

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Full Clinical Trial Report Incidental diagnosis of lung cancer on chest CT scan performed for suspected or documented COVID-19 infection: https://pubmed.ncbi.nlm.nih.gov/38663250/?utm_source=Feedly&utm_medium=rss&utm_campaign=None&utm_content=1B1L42DK3a-JWCV4P_PtHHBmWjwBLFNcDXsYJkbqjQD0Ca7UQh&fc=None&ff=20240426043029&v=2.18.0.post9+e462414

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