Study Title:
Intraoperative intravenous versus periarticular injection of glucocorticoids in improving clinical outcomes after total knee arthroplasty: A prospective, randomized and controlled study
Abstract:
Background: Glucocorticoids are commonly used for pain relief after total knee arthroplasty (TKA), but the best way to administer them is still debated. This study compares the effectiveness of glucocorticoids given intravenously versus through periarticular injection on clinical outcomes.
Methods: 114 patients were randomly assigned to receive either intravenous (IV) glucocorticoids (n = 57) or periarticular injection (PI) (n = 57) during TKA. Clinical outcomes were measured using various assessments.
Results: The PI group had lower pain scores while walking on the second day after surgery compared to the IV group. Other measures of pain, inflammation, knee function, and complications did not show significant differences between the two groups.
Conclusions: Periarticular injection of glucocorticoids has a similar pain-relieving effect as intravenous administration after TKA, and may be even more effective on the second postoperative day. Additionally, periarticular injection does not increase the risk of complications for patients.
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