Study Overview
This study explored the use of ketamine combined with morphine for pain relief after colorectal surgery. It compared this combination (PCA ketamine-morphine) to morphine alone (PCA morphine).
Study Design
The research was a double-blind, randomized controlled trial conducted at a large hospital, involving 60 patients who had elective colorectal surgery.
Patient Groups
Patients were divided into two groups:
- Group A: Received PCA ketamine-morphine (0.5:0.5 mg/mL)
- Group B: Received PCA morphine (1 mg/mL)
Main Findings
Key results from the study included:
- At rest, Group A reported significantly lower pain scores at 24 hours (1.10 vs. 2.10).
- Both groups had similar total PCA demands.
- Group A used less morphine overall, with 24.7 mg compared to 48.9 mg at 24 hours and 38.3 mg compared to 77.8 mg at 48 hours.
- Side effects and overall satisfaction were similar in both groups.
Conclusions
The combination of PCA ketamine-morphine is as effective as PCA morphine alone for post-operative pain management in colorectal surgery. It also significantly reduces the amount of morphine needed.
Opportunities for Improvement
Based on these results, clinics can:
- Set measurable goals for using PCA ketamine-morphine to enhance pain management.
- Explore AI tools that align with specific clinical needs to track pain management outcomes.
- Start pilot projects to implement these findings and monitor results effectively.
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