Conditions: Low-grade Glioma
Interventions: Drug: Tovorafenib
Sponsors: Daniel Morgenstern; The Hospital for Sick Children
Recruiting
Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas
AI-Powered Health Tools
Interactive AI Tools to Help You Understand Your Health
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Is your protein in urine normal? Upload lab result for AI interpretation
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Solutions for Smart Healthcare
Clinical Research
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“Enhancing ERCP Outcomes: The Benefits of Hypnosis Combined with Sedoanalgesia”
Understanding the Study Results This study explored how hypnosis combined with sedation can improve patient care during a procedure called Endoscopic Retrograde Cholangiopancreatography (ERCP). ERCP is used to diagnose and…
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Brain functional connectivity changes on fMRI in patients with chronic pelvic pain treated with the Neuro Emotional Technique: a randomised controlled trial
Background Chronic pelvic pain is a significant issue for many women, affecting their quality of life. The Neuro Emotional Technique (NET) is a new approach that aims to help reduce…
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Late Gadolinium Enhancement of Nonischemic Cardiomyopathy at 5.0 T versus 3.0 T: A Crossover Design Study
Late Gadolinium Enhancement of Nonischemic Cardiomyopathy Study Study Overview This study compares the effectiveness of 5.0-T and 3.0-T cardiac MRI in visualizing late gadolinium enhancement (LGE) in patients with nonischemic…
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Intranasal Insulin Diminishes Postoperative Delirium and Elevated Osteocalcin and Brain Derived Neurotrophic Factor in Older Patients Undergoing Joint Replacement: A Randomized, Double-Blind, Placebo-Controlled Trial
Intranasal Insulin Reduces Postoperative Delirium in Older Patients Study Overview This study explored how intranasal insulin affects older patients after joint replacement surgery. It aimed to see if this treatment…
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Home-Monitoring Vision Tests to Detect Active Neovascular Age-Related Macular Degeneration
“`html Summary of Clinical Trial Report Background Neovascular age-related macular degeneration (nAMD) treatments require long-term follow-up of disease activity, which can be burdensome for patients and caregivers. Home-monitoring could alleviate…
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Use of tourniquet in anterior cruciate ligament reconstruction: Is it truly necessary? A prospective randomized clinical trial
Is a Tourniquet Necessary for ACL Reconstruction? A Study Overview Purpose of the Study This study looked at whether using a tourniquet during arthroscopic anterior cruciate ligament (ACL) reconstruction is…
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Impact of Digital Therapy on Male LUTS: Key Insights from the BEST Trial
Understanding the BEST Trial Results What is the BEST Trial? The BEST trial looked at how well a digital health app called Kranus Lutera helps men with lower urinary tract…
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Measuring clinically relevant change in apathy symptoms in ADMET and ADMET 2
Measuring Change in Apathy Symptoms in Alzheimer’s Disease Trials Study Overview This study focused on participants with Alzheimer’s disease (AD) to determine the minimal clinically important difference (MCID) in apathy…
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Primary Care Professionals’ Willingness to Treat Opioid Use Disorder vs Type 2 Diabetes: Key Insights
Understanding the Study Results This study looked at how willing primary care professionals (PCPs) are to treat patients with opioid use disorder (OUD) compared to those with type 2 diabetes.…
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Nutritional Counseling Based on Mindful Eating for the Eating Behavior of People Living with Overweight and Obesity: A Randomized Clinical Trial
Nutritional Counseling Based on Mindful Eating for Overweight and Obesity Study Overview This study looked at how Mindful Eating counseling affects the eating habits of people with overweight and obesity.…
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Gadobutrol vs. Meglumine Gadoterate: Key Insights for MRI of Pituitary Macroadenomas
Summary of the Study This study looked at two types of contrast agents used in MRI scans for patients with pituitary macroadenomas, which are tumors in the pituitary gland. The…
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Autologous Cord Blood Therapy in Extremely Preterm Infants: Early Neurodevelopment Outcomes
Understanding the Study Results for Extremely Preterm Infants What Was the Study About? This study looked at the effects of using a type of treatment called autologous umbilical cord blood…
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Efficacy of Oatmeal Lotion in Treating Mild to Moderate Psoriasis: A Clinical Study
Understanding the Study Results This study looked at a lotion made from oats to help people with sensitive skin and mild to moderate psoriasis. Psoriasis is a skin condition that…
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Short-term structured dietary and exercise interventions delay diabetes onset in prediabetic patients: a prospective quasi-experimental study
Study Overview This study explored how structured dietary and exercise interventions can help delay diabetes in prediabetic patients. Prediabetes increases the risk of developing diabetes, and the researchers aimed to…
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Evaluating Disease Activity Instruments in Peripheral Spondyloarthritis: Key Insights for Clinicians
Understanding the Trial Results This research looked at how well different tools measure disease activity in patients with peripheral spondyloarthritis (pSpA). The study used data from the CRESPA trial, which…
