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Itinai.com biomedical laboratory close up still scene close u e4996bf4 1113 41b3 8fdd 0d1e6c918068 0

The efficacy of narrowband ultraviolet B phototherapy combination with tofacitinib in the treatment of vitiligo: a randomized controlled trial

Study Overview

This clinical trial focused on the effectiveness of using tofacitinib along with narrowband ultraviolet B (UVB) therapy for treating vitiligo, a skin condition that causes loss of skin color.

Methodology

A total of 136 patients with vitiligo were divided into two groups: one group received only UVB therapy, while the other group received UVB therapy plus tofacitinib. The patients were monitored for 24 weeks, and various measures were taken to assess their treatment results.

Results

The results showed that significantly more patients who received the combination treatment (tofacitinib and UVB) improved compared to those who only received UVB therapy. Additionally, this group had lower scores for skin severity and quality of life impacts, as well as reduced levels of certain inflammatory markers.

Key Takeaways

The findings indicate that combining tofacitinib with UVB therapy may be a more effective treatment option for vitiligo, leading to better recovery and lower inflammation.

Practical Applications

  • Define Measurable Outcomes: Set clear goals to assess the effectiveness of the combined treatment in clinical settings.
  • Choose Suitable AI Tools: Select AI solutions that can support the implementation of this therapy effectively.
  • Implement Gradually: Start with pilot projects to track the results of the combined treatment using AI tools to analyze real-world effectiveness.

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