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Itinai.com close up of doctor hands doing procedure for patie b62daafd ae78 4416 b629 6e501ccde339 0

The Genetic Information and Family Testing (GIFT) study: trial design and protocol

Background

There is a strong need to help patients with inherited cancer risks and their family members. Engaging these patients can help their families understand genetic risks better. The Genetic Information and Family Testing (GIFT) Study aims to support patients with inherited cancer risks and assist their relatives in starting genetic risk evaluations, including home genetic testing options.

Methods/Design

The GIFT Study is a clinical trial designed to test a new online tool called the Family Genetic Health Program. This tool helps families communicate about genetic health issues. We are focusing on patients diagnosed with cancer in Georgia and California who have inherited genetic mutations. These patients can invite their family members to participate in the study.

Participants will be randomly assigned to different groups, and everyone will receive some form of support. This includes access to an online platform with information about genetic testing and options for relatives to receive genetic testing. We are also comparing two different types of support: personalized online tools versus tools with help from a trained navigator, and we are looking at the cost of genetic testing ($50 or free).

Discussion

The GIFT Study serves as a model for how to effectively provide genetic risk evaluation in communities for families with hereditary cancer syndromes. The findings from this study will help improve future approaches to genetic risk evaluation.

Trial Registration

This study is registered under the identifier NCT05552664 at ClinicalTrials.gov since September 20, 2022.

Opportunities Based on Trial Data

Analyze the GIFT study to identify measurable outcomes and set clear goals for clinics and patients. Select AI tools that fit the needs of the clinical setting and choose tailored solutions for specific tasks. Implement these solutions step by step, starting with a pilot project and tracking results to understand their real-world impact.

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