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Study on Fosaprepitant for Chemotherapy-Induced Nausea and Vomiting
Practical Solutions and Value:
Two doses of fosaprepitant were studied for preventing nausea and vomiting caused by three-day cisplatin-based chemotherapy in lung cancer patients. This study aimed to explore the effectiveness and safety of using two doses of fosaprepitant for this purpose.
The study involved 204 participants from nine hospitals, and it was found that the two doses of fosaprepitant were not only safe but also more effective in preventing chemotherapy-induced nausea and vomiting compared to using one dose.
The patients who received two doses of fosaprepitant had significantly more days without experiencing nausea and vomiting. Additionally, their quality of life was better, as indicated by the FLIE questionnaire.
These findings support the use of two doses of fosaprepitant as a safe and more effective approach for protecting patients from chemotherapy-induced nausea and vomiting.
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