[(18)F]FDG PET/CT performs better than CT in determining the bone biopsy site : randomized controlled clinical trial

Better Imaging for Bone Biopsies

Study Overview

A recent clinical trial found that [18F]FDG PET/CT is more effective than CT for locating biopsy sites in patients with suspected bone metastases. This study involved 273 patients treated between January 2020 and March 2021.

Key Findings

  • Higher Accuracy: [18F]FDG PET/CT showed an accuracy of 97.08% compared to 90.44% for CT.
  • Better Sensitivity: Sensitivity was 98.76% for [18F]FDG PET/CT, while CT had 92.22%.
  • Lower Second Biopsy Rate: Only 2.19% of patients needed a second biopsy with [18F]FDG PET/CT, compared to 5.15% with CT.
  • Faster Diagnosis: The average diagnostic time was shorter for [18F]FDG PET/CT (18.33 days) versus CT (21.28 days).
  • Cost-Effective: The cost for [18F]FDG PET/CT was 11,428.35 yuan, while CT was 13,287.52 yuan, making PET/CT the more economical choice.

Conclusion

[18F]FDG PET/CT is not only more effective but also more cost-efficient than CT for determining biopsy sites in suspected bone metastases.

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