Microvascular Recovery with Ultrasound in Myocardial Infarction Post-PCI Trial
Abstract
Purpose: This study aimed to assess the effectiveness of post-PCI sonothrombolysis in patients with acute anterior wall STEMI.
Methods: A randomized controlled trial was conducted on 50 patients who underwent continuous microbubble infusion following successful PCI. Sonothrombolysis was applied in the treatment group. MRI was used to evaluate differences in infarct size, LVEF, and MVO.
Results: Sonothrombolysis did not significantly reduce infarct size or MVO at 48 hours post-PCI. However, LVEF improvement was observed in the sonothrombolysis group at 6-8 weeks follow-up.
Conclusion: Post-PCI sonothrombolysis had minimal effect on reducing infarct size but improved left ventricular systolic function in patients with acute anterior wall STEMI.
PMID:38889076 | DOI:10.1111/echo.15860
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