Comparative Evaluation of Regain of Consciousness in Dexmedetomidine-Propofol versus Ketamine-Propofol in the Pediatric Cardiac Catheterization Procedure under Sedation using BIS Monitoring: A Randomized Prospective Study

Comparative Evaluation of Sedation in Pediatric Cardiac Procedures

Study Overview

This study compares two sedation methods for children with congenital heart diseases undergoing cardiac catheterization: Dexmedetomidine-Propofol (DP) and Ketamine-Propofol (KP). The aim was to determine which combination allows for faster recovery of consciousness.

Key Findings

  • Faster Recovery: Children in the KP group regained consciousness significantly faster (11.02 minutes) than those in the DP group (21.62 minutes).
  • Better Monitoring: BIS values (a measure of sedation depth) were lower in the DP group compared to the KP group, indicating differences in sedation levels.
  • Comparable Drug Usage: The total doses of propofol and fentanyl used were similar in both groups, without any significant side effects reported.

Conclusion

The Ketamine-Propofol combination is beneficial for faster recovery during pediatric cardiac catheterization procedures.

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