A Comparative Study of Esketamine-Propofol vs Sufentanil-Propofol for Breast Surgery
Study Overview
This study investigates two anesthesia methods for patients undergoing breast surgery: esketamine-propofol and sufentanil-propofol. The goal is to find out which method is safer and more effective for pain relief and sedation.
Study Purpose
Minimally invasive rotary resection (MIRR) is vital for breast tumor treatment. However, there’s no clear best option for intravenous anesthesia. Esketamine may be a helpful addition to propofol sedation.
Patient Involvement
Ninety patients were randomly chosen to receive either sufentanil-propofol or esketamine-propofol. The main focus was on the occurrence of hypoxia (low oxygen levels). Other factors like respiratory depression, airway interventions, satisfaction scores, and recovery time were also monitored.
Key Results
- The esketamine group had a significantly lower hypoxia rate (17.5%) compared to the sufentanil group (39%).
- Subclinical respiratory depression occurred in 32.5% of the esketamine group and 56.1% of the sufentanil group.
- More airway interventions were needed for the sufentanil group.
- Patients in the sufentanil group received more mask-assisted ventilation due to hypoxia.
- Hemodynamic stability was better with esketamine.
- No significant differences were found in recovery time, satisfaction, or side effects between the two groups.
Conclusions
Esketamine-propofol anesthesia offers a lower risk of hypoxia compared to sufentanil-propofol, while keeping patient satisfaction and recovery time similar. Its stability benefits make it a valuable option for procedures needing reliable respiratory support.
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