A synbiotic mixture for the management of infantile colic: A randomized trial

A Synbiotic Mixture for Managing Infantile Colic

Study Overview

This study investigates the effectiveness of a synbiotic (Bactecal D Liquid) for infants experiencing colic, which is characterized by excessive crying and irritability. A total of 68 infants were involved in a randomized trial, where they received either one or two doses of the synbiotic daily for 28 days.

Key Findings

  • Improved Quality of Life: Caregiver quality of life scores significantly increased after just 7 days of treatment.
  • Significant Reductions: The number of crying episodes, total crying time, gassiness, and ‘balling of fists’ were all significantly lower after 28 days.
  • Quick Results: The benefits were noticeable much earlier than expected, within one week of starting the treatment.

What We Learned

  • Effective Treatment: The synbiotic was effective in managing infant colic symptoms.
  • No Difference in Doses: One dose was as effective as two doses.
  • Feeding Independence: Improvements were observed regardless of whether the infants were breastfed, formula-fed, or mixed-fed.

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