An optimized strategy triggered at the 2nd immunization visit to prevent HIV acquisition by breastfeeding: a phase 2 trial in Burkina Faso (PREVENIR-PEV)

An Optimized Strategy to Prevent HIV Transmission through Breastfeeding

Study Overview

A clinical trial called PREVENIR-PEV was conducted in Burkina Faso to prevent HIV transmission from mothers to infants through breastfeeding. The trial focused on identifying undiagnosed infants living with HIV during the 2nd immunization visit.

Key Findings

During the trial, 118 mothers living with HIV were identified, and 102 mother/infant pairs had their infants tested for HIV. Six infants were diagnosed with HIV, and 96 HIV-exposed uninfected infants were followed for 10 months. No HIV transmission occurred in infants who received extended postnatal prophylaxis with lamivudine.

Practical Solutions

The prevention package integrated into existing care in Burkina Faso was found to be safe and feasible, even in low HIV prevalence settings. This approach could be valuable in similar settings worldwide.

Value of Clinical Trials

Clinical trials play a crucial role in developing safe treatments. Implementing the findings of trials like PREVENIR-PEV into routine medical practice can improve patient care and outcomes.

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By leveraging AI, clinics can improve workflows, reduce paperwork, and ultimately enhance patient outcomes. To learn more about how AI can benefit healthcare practices, visit aidevmd.com.

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