Effectiveness of Flaxseed and Fasting Mimicking Diet in Managing MASLD
Study Overview
This study explored how combining flaxseed and a fasting mimicking diet (FMD) affects patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). While both treatments have shown benefits individually, their combined effect was unclear.
Study Design
Conducted over 12 weeks, this randomized trial involved 100 MASLD patients divided into four groups:
- Control Group: Received lifestyle modification advice.
- Flaxseed Group: Consumed 30 g of flaxseed powder daily.
- FMD Group: Fasted for 16 hours each day.
- Combination Group: Received both flaxseed and FMD.
Key Findings
All intervention groups showed:
- Decreased levels of triglycerides, total cholesterol, fasting blood glucose, insulin, hs-CRP, and liver enzymes.
- Reduction in hepatic steatosis score, although not significantly compared to the control group.
- Significant decrease in hepatic fibrosis score compared to the control group.
Conclusion
The study concluded that combining FMD with flaxseed is not more effective than using either treatment alone for managing MASLD.
Importance of Clinical Trials
Clinical trials are essential for developing safe and effective treatments. They help translate research findings into practical healthcare solutions.
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