Efficacy of seventh generation bonding agents as desensitizers in patients with dentin hypersensitivity: a randomized clinical trial

Efficacy of Seventh Generation Bonding Agents as Desensitizers in Patients with Dentin Hypersensitivity: A Randomized Clinical Trial

Background

Dentin hypersensitivity (DH) causes intense, transient pain in a significant portion of the global population, especially those aged 20-40. This study evaluates the effectiveness of seventh-generation dentin bonding agents in reducing DH compared to a control group using fluoride varnish.

Methods

A randomized clinical trial was conducted at Dow University of Health Sciences, Karachi, Pakistan, with 105 DH patients divided into three groups: two using different bonding agents and one control group using fluoride varnish. Discomfort and sensitivity scores were recorded at various intervals over a one-month period.

Results

All materials showed a significant reduction in discomfort and sensitivity immediately after one week and over one month compared to baseline scores. No material proved superior over the one-month observation period. The study also provided insights into dental hygiene practices and sensitivity patterns.

Conclusion

The study demonstrates that the bonding agents and fluoride varnish are equally effective in reducing dentin hypersensitivity over a one-month period. The findings highlight the potential of fluoride varnishes as a less technique-sensitive and cost-effective option for treating DH, offering valuable insights for future research and clinical practice.

Trial Registration

NCT04225247 (Retrospectively registered on 13/01/2020)

Value in Clinical Practice

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