Evaluation of Treatment for Pterygium

Study Overview: This study investigates the benefits of modified limbal stem cell transplantation (Modified LSC) combined with bandage contact lens (BCL) implantation in treating pterygium.

Objective:

To assess how effective Modified LSC and BCL are in improving outcomes after pterygium surgery.

Methods:

A total of 479 patients with primary pterygium participated in this study from March 2019 to March 2023. They were divided into three groups:

Group A: 89 patients—no surgery, just outpatient follow-up.
Group B: 195 patients—received LSC transplantation with sutures and BCL.
Group C: 195 patients—received Modified LSC transplantation with BCL.

We compared their symptoms, healing progress, complications, tear film stability, intraocular pressure, inflammation, and vision quality over time.

Results:

Key Findings:

Group C showed quicker recovery and fewer symptoms compared to Group B.
Tear film break-up time improved significantly in Group C after surgery, almost matching Group A by three months.
Intraocular pressure was highest in Groups B and C after one week due to steroid drops but decreased in Group C by one month.
Inflammatory markers were lower in Group C compared to Group B.
Group C had better vision and quality of life scores at one year after surgery.

Conclusion:

Modified LSC transplantation with BCL is a more effective treatment for pterygium and is recommended for broader use.

Value of Clinical Trials

Clinical trials are essential for developing safe and effective treatments. It’s important to integrate these findings into everyday medical practice.

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