Evaluation of the effect of adjunctive diode laser application on peri-implant crevicular fluid biomarker levels: a randomized controlled trial

Evaluation of Diode Laser Therapy for Peri-Implantitis

Objective

To assess the effectiveness of diode laser therapy as an adjunct to non-surgical mechanical therapy in managing peri-implantitis.

Methods

A cohort of 27 participants with peri-implantitis diagnosis received either diode laser therapy or non-laser treatment. Clinical parameters and peri-implant crevicular fluid (PICF) samples were evaluated at baseline, 3 months, and 6 months. Biomarker levels in the PICF were measured using enzyme-linked immunosorbent assay.

Results

Both groups showed improvements in clinical and biochemical parameters over time. Differences were observed between the groups at the 3-month follow-up, particularly in certain biomarker levels, but not at the 6-month follow-up.

Conclusions

Diode laser therapy appears to be beneficial as an adjunct to non-surgical treatment for early-stage peri-implantitis. Certain biomarkers may be useful for assessing the efficacy of peri-implantitis treatment.

Clinical Relevance

Using diode laser therapy alongside non-surgical treatment may lead to better clinical and immunological improvements during the early healing period. However, no long-term differences were observed between the two methods.

Practical Solutions and Value

Clinical trials are essential for developing safe and effective treatments. Our AI-driven platform, DocSym, consolidates clinical standards and research, making it easier for clinicians to access relevant knowledge. Additionally, our mobile apps support scheduling, treatment monitoring, and telemedicine, streamlining operations and improving patient care.

AI Products for Business or Try Custom Development

AI Sales Bot

Welcome AI Sales Bot, your 24/7 teammate! Engaging customers in natural language across all channels and learning from your materials, it’s a step towards efficient, enriched customer interactions and sales

AI Document Assistant

Unlock insights and drive decisions with our AI Insights Suite. Indexing your documents and data, it provides smart, AI-driven decision support, enhancing your productivity and decision-making.

AI Customer Support

Upgrade your support with our AI Assistant, reducing response times and personalizing interactions by analyzing documents and past engagements. Boost your team and customer satisfaction

AI Scrum Bot

Enhance agile management with our AI Scrum Bot, it helps to organize retrospectives. It answers queries and boosts collaboration and efficiency in your scrum processes.