Itinai.com close up of doctor hands doing procedure for patie b62daafd ae78 4416 b629 6e501ccde339 2
Itinai.com close up of doctor hands doing procedure for patie b62daafd ae78 4416 b629 6e501ccde339 2

Five-Day Treatment with B. licheniformis Along with Classical Vancomycin Treatment Was Effective in Preserving Gut Microbiota in Patients with Clostridioides difficile Infection

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Background and Objectives

Clostridioides difficile infection (CDI) is a serious type of diarrhea often acquired in hospitals. This study looked at how the probiotic Bacillus licheniformis (B. licheniformis) can help maintain healthy gut bacteria in patients with CDI.

Study Overview

This research was conducted at six academic centers in Korea. It involved patients diagnosed with mild to moderate CDI, who were treated with vancomycin, a common antibiotic, for two weeks. Along with vancomycin, some patients received B. licheniformis for five days, while others received a placebo.

Results

A total of 35 participants were included in the study, with 16 receiving B. licheniformis and 19 receiving the placebo. Key findings included:

  • Before treatment, both groups had similar gut bacteria diversity.
  • After five days, the group receiving B. licheniformis maintained their gut bacteria diversity.
  • In contrast, the placebo group showed a decrease in gut bacteria diversity.

Conclusion

Adding B. licheniformis to vancomycin treatment effectively preserved gut microbiota in patients with CDI.

Opportunities for Clinics

Define Measurable Outcomes

Set clear goals to measure the success of treatments in preserving gut health.

Select AI Tools That Fit Clinical Needs

Choose AI solutions that are specifically designed for managing patient care and treatment tracking.

Implement Step by Step and Expand

Start with a small pilot project, monitor the results, and gradually expand the use of AI solutions based on the findings from this study.

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