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Itinai.com biomedical laboratory close up still scene close u e4996bf4 1113 41b3 8fdd 0d1e6c918068 3

Home-Monitoring Vision Tests to Detect Active Neovascular Age-Related Macular Degeneration

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Summary of Clinical Trial Report

Background

Neovascular age-related macular degeneration (nAMD) treatments require long-term follow-up of disease activity, which can be burdensome for patients and caregivers. Home-monitoring could alleviate this burden and free up clinic capacity.

Objective

The study aimed to assess the effectiveness of 3 vision home-monitoring tests in detecting active nAMD compared to traditional hospital follow-up for monitoring disease activity after treatment.

Methods

  • Diagnostic test accuracy study with 297 patients from 6 UK hospital eye clinics
  • Participants aged 50 years and older with at least 1 eye treated for active nAMD
  • Evaluated home-monitoring tests: KeepSight Journal (KSJ), MyVisionTrack (mVT), and MultiBit (MBT)
  • Raw scores between hospital follow-ups were averaged

Findings

Results showed that none of the home-monitoring tests provided satisfactory accuracy in identifying active nAMD diagnosed during hospital follow-up. Only the KSJ summary score was associated with lesion activity.

Implications

Implementing these home-monitoring tests with ophthalmologists only reviewing positive results could lead to missing most active lesions and risking unnecessary sight loss.

Conclusion

The study suggests that the evaluated home-monitoring vision tests may not be reliable for identifying active nAMD. Further research and development of alternative monitoring solutions may be necessary.

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