Nontargeted Metabolomic Profiling Analysis of Corn Silk Treatment for Type 2 Diabetes Mellitus
Medicine (Baltimore). 2024 Aug 16;103(33):e39396
Patients with newly diagnosed type 2 diabetes mellitus (T2DM) were studied to understand the effects of corn silk treatment. The study found that patients receiving corn silk experienced a significant decrease in glycosylated hemoglobin and fasting blood glucose after 3 months of treatment. An untargeted metabolomics study identified 73 differential metabolites, indicating that corn silk water extract may reduce blood glucose in T2DM patients through multiple pathways, including oxidative phosphorylation and purine metabolism.
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