Tissue Doppler Echocardiography and Long-Term Cardiovascular Mortality
Study Overview
This study examines how tissue Doppler echocardiography can predict long-term cardiovascular mortality in hypertensive patients based on data from the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).
Key Findings
- Background: Left ventricular diastolic function, evaluated through tissue Doppler echocardiography, has shown to predict cardiovascular events within 4 years in hypertensive patients.
- Long-Term Prediction: The study aimed to see if these findings also apply to predicting cardiovascular deaths over 20 years.
Methodology
The study involved 506 hypertensive patients, with follow-up data linked to national statistics. Various echocardiography measurements were taken and analyzed against cardiovascular mortality rates.
Results
- Out of 506 patients, 200 (40%) died over the 20-year period, with 60 (12%) of these deaths linked to cardiovascular issues.
- A decrease in the e’ measurement was linked to higher cardiovascular mortality, showing a significant risk increase per 1 cm/s decrease.
- A higher E/e’ ratio also indicated increased cardiovascular mortality risk.
Conclusions
The study concludes that impaired left ventricular diastolic function, as measured by tissue Doppler echocardiography, is a strong predictor of increased cardiovascular mortality over 20 years in hypertensive patients.
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