Longitudinal neurofunctional changes in medication overuse headache patients after mindfulness practice in a randomized controlled trial (the MIND-CM study)

Longitudinal Neurofunctional Changes in Medication Overuse Headache Patients After Mindfulness Practice

Key Findings

Mindfulness practice, when added to standard medication, led to significant reduction in headache frequency and improvement in clinical variables in Chronic Migraine associated with Medication Overuse Headache (CM-MOH) patients.

The study revealed that patients practicing mindfulness showed increased functional connectivity in brain networks associated with pain perception, body-awareness, and cognitive processing of pain information.

Practical Solutions and Value

These findings highlight the therapeutic potential of mindfulness in managing chronic pain and negative emotions in CM-MOH patients.

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