Understanding the Trial Results
The study looked at how a specific measure called net water uptake (NWU) affects the success of a treatment called endovascular thrombectomy (EVT) for patients who have had a stroke with large brain damage. Here’s what they found:
What Worked?
- Patients with lower NWU (less than 15%) who received EVT showed better recovery outcomes compared to those who only received standard medical treatment.
- EVT significantly improved chances of better functional scores at 90 days for these patients.
What Didn’t Work?
- For patients with higher NWU (15% or more), EVT did not provide any additional benefits over standard treatment alone.
How Does This Help Patients and Clinics?
- Hospitals can use NWU measurements from CT scans to identify which patients are likely to benefit from EVT.
- This helps doctors make better treatment decisions, potentially leading to improved outcomes for patients with strokes.
Real-World Opportunities
- Hospitals can implement routine NWU assessments in stroke patients to guide treatment choices.
- Doctors can use this information to discuss treatment options more effectively with patients and their families.
Measurable Outcomes to Track
- Monitor the percentage of patients with low NWU who receive EVT and their recovery scores at 90 days.
- Track overall patient satisfaction and functional improvements post-treatment.
AI Tools to Consider
- AI algorithms can help automate the measurement of NWU from CT scans, making it quicker and easier for doctors to make decisions.
Step-by-Step Plan for Clinics
- Start by training staff on how to measure NWU from CT scans.
- Implement NWU assessments for all stroke patients in the emergency department.
- Evaluate the outcomes of patients based on NWU and adjust treatment protocols accordingly.
- Gradually expand the use of NWU assessments to other departments and treatment protocols.
For more detailed information about the study, you can visit the research link here: ClinicalTrials.gov Identifier: NCT03094715.



























