Itinai.com light and shadow chase in a bright clinical trial 46d6fec8 e34f 4900 920c bc826aa5cb79 2
Itinai.com light and shadow chase in a bright clinical trial 46d6fec8 e34f 4900 920c bc826aa5cb79 2

A digital therapeutic for people with borderline personality disorder in Germany (EPADIP-BPD): a pragmatic, assessor-blind, parallel-group, randomised controlled trial

Background

Less than 25% of people with borderline personality disorder (BPD) get the recommended therapy. Digital tools can help close this gap. This study tested a digital therapy called priovi for BPD.

Methods

We ran a study in Germany with patients diagnosed with moderate to severe BPD. Participants were at least 18 years old, had a safety plan for crises, and agreed to join the study. Those with substance use or psychotic disorders were not included. Patients were randomly assigned to either use the priovi digital therapy along with their usual treatment or just their usual treatment. The study was designed to keep researchers unaware of which group each patient was in until after the results were analyzed. All patients had access to standard care, and the control group received self-help materials for BPD. We measured the effectiveness of the therapy after 3 months using a specific symptom checklist and tracked any serious side effects through online surveys.

Findings

From May to October 2022, we screened 1,766 patients and included 580 in the study. At the 3-month mark, 12% of the priovi group and 5% of the control group dropped out. The average age of participants was 29 years. Our analysis showed that those using priovi had better outcomes than those who did not (p=0.0005). Importantly, there were fewer suicide attempts in the priovi group (7 attempts) compared to the control group (21 attempts), indicating a safer option (p=0.0081).

Interpretation

This study suggests that the priovi digital therapy is effective and does not raise safety concerns for people with BPD.

Opportunities Based on Trial Data

Define Measurable Outcomes

Set clear goals for using digital therapy in clinics and for patients with BPD.

Select AI Tools That Fit Clinical Needs

Choose AI solutions that are tailored to specific tasks in managing BPD.

Implement Step by Step and Expand

Start with a pilot project, track results using AI solutions, and measure the real-world impact of the priovi therapy.

Contact Us for AI Solutions in Medical Management

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