A randomized controlled clinical trial of concentrated growth factor combined with sodium hyaluronate in the treatment of temporomandibular joint osteoarthritis

Study Summary: Concentrated Growth Factor and Sodium Hyaluronate for Temporomandibular Joint Osteoarthritis

Objective

To assess the impact of concentrated growth factor (CGF) combined with sodium hyaluronate (SH) on temporomandibular joint osteoarthritis (TMJOA).

Methods

Sixty TMJOA patients were divided into control and experimental groups. The experimental group received CGF + SH, while the control group received SH only. Pain scores, clinical dysfunction index, and condylar changes were recorded at various intervals.

Results

– The experimental group showed significantly lower pain scores and improved clinical function compared to the control group.
– Condylar bone cortex repair was notably better in the experimental group.
– Three-dimensional reconstruction confirmed the positive CBCT findings.

Conclusion

CGF combined with SH effectively treats TMJOA, reducing muscle and TMJ pain, improving TMJ function, and promoting bone repair.

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