Effect of antenatal use of high energy nutritional supplements on cardio metabolic risk markers in underweight primi gravidas; a randomized controlled trial

Effect of Nutritional Supplements During Pregnancy

Study Overview

This study explores how high energy nutritional supplements can impact health markers related to heart and metabolism in underweight first-time pregnant women.

Background

Pregnancy increases nutritional needs, and inadequate maternal nutrition can lead to higher risks of heart and metabolic issues. This research is important as it focuses on the benefits of nutritional supplements for underweight mothers.

Methodology

From April 2018 to August 2019, a randomized controlled trial was conducted in Khyber Pakhtunkhwa, Pakistan. Thirty-six participants were divided into two groups: one received the high energy supplement ‘MAAMTA’ and the other received a placebo. Both groups continued their regular prenatal care and diet from their first antenatal visit until one week after giving birth. Measurements of body size and blood samples for insulin, fasting blood glucose, and lipid levels were taken at different stages of the study.

Results

The analysis showed significant improvements in:

  • Insulin Levels: Improved significantly over time.
  • Insulin Resistance: Decreased significantly.
  • LDL Levels: Reduced significantly.

Conclusion

Using high energy nutritional supplements can enhance insulin levels and sensitivity in underweight first-time pregnant women.

Trial Registration

For more details, visit ClinicalTrials.gov.

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