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Itinai.com close up of doctor hands doing procedure for patie b62daafd ae78 4416 b629 6e501ccde339 0

Efficacy of topical tacrolimus 0.03% ointment in combination with microneedling versus topical phenytoin 2% cream in combination with microneedling for the treatment of non-segmental facial vitiligo

Aim of the Study

The study aimed to compare the effectiveness and safety of two treatments for non-segmental facial vitiligo: microneedling with tacrolimus 0.03% ointment and microneedling with phenytoin 2% cream.

Materials and Methods

This study involved 40 patients with non-segmental facial vitiligo. They were split into two groups of 20. One group received microneedling with tacrolimus, while the other group received microneedling with phenytoin. Treatments were given every two weeks for six months, followed by a three-month follow-up period.

Results

Both groups had similar demographic and disease characteristics. However, patients treated with microneedling and tacrolimus showed better clinical improvements and higher satisfaction levels compared to those treated with phenytoin. These differences were not statistically significant.

Conclusion

The study suggests that tacrolimus 0.03% ointment combined with microneedling may provide better results than phenytoin 2% cream. Phenytoin also appears to be a viable option for treating non-segmental vitiligo.

Practical Healthcare Results and Solutions

Measurable Outcomes

Clinics should focus on tracking the improvement in skin color and patient satisfaction to evaluate the effectiveness of these treatments.

AI Tools for Clinical Needs

Select AI solutions that can help monitor patient progress and enhance treatment plans based on individual responses to microneedling and topical ointments.

Implementation Steps

Start with a pilot project that uses AI to track treatment outcomes. Assess the real-world impact of both treatment options to inform future practices.

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