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Itinai.com an advertising picture for medical analysis labora e23355f1 1375 4542 a767 fc92f774dc1f 3

PRERISK Study: A Randomized Controlled Trial Evaluating a sFlt-1/PlGF-Based Calculator for Preeclampsia Hospitalization

Hypertension Study Overview

This study focused on a new model called the PRERISK calculator, which uses specific health indicators to predict complications in pregnant women with preeclampsia. The aim was to see if using this model could reduce hospital admissions without increasing health risks for mothers and their babies.

Study Method

The research was conducted in five Dutch hospitals. Women with suspected or confirmed preeclampsia were divided into two groups: one used the PRERISK score to guide hospital admissions, while the other received standard care without this score. The study looked at two main outcomes: the rate of complications and the number of women who had fewer hospital days.

Key Findings

In total, 442 women were in the intervention group and 435 in the control group. The results showed:

  • Complications occurred in 41.6% of the intervention group and 39.5% of the control group.
  • Only 23.6% of the intervention group had a hospitalization ratio of 0.05 or lower, compared to 26.3% in the control group.

These results suggest that using the PRERISK score did not reduce hospital admissions and may have even led to more complications in some cases.

Conclusions

The study concluded that routine use of the PRERISK score for managing preeclampsia is not recommended, as it does not help decrease hospital stays.

Opportunities for Improvement

Based on the trial data, clinics can:

  • Define clear goals for managing preeclampsia.
  • Identify measurable outcomes to track progress.
  • Select AI tools that meet specific clinical needs for better patient management.
  • Implement changes gradually, starting with pilot projects and tracking results.

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