Time-restricted eating with or without a low-carbohydrate diet improved myocardial status and thyroid function in individuals with metabolic syndrome: secondary analysis of a randomized clinical trial

Time-restricted eating and low-carbohydrate diet improve heart and thyroid health in metabolic syndrome

Summary

Researchers found that time-restricted eating (TRE) and low-carbohydrate diet (LCD) can significantly improve heart and thyroid function in people with metabolic syndrome (MetS). The study involved 169 MetS patients, who were randomly assigned to the LCD group, the 8-hour TRE group, or a combination of both for 3 months. After the interventions, markers of heart and thyroid health showed positive changes, indicating metabolic benefits for MetS patients.

Key findings include reductions in lactate dehydrogenase, creatine kinase MB, hydroxybutyrate dehydrogenase, and free triiodothyronine (FT3), as well as increases in free thyroxine (FT4). Moreover, the combination group experienced decreases in thyrotropin and T3, while T4, thyroglobulin antibodies (TgAb), and thyroid microsomal antibodies (TMAb) increased. TRE was particularly associated with positive changes in thyroid function, while no significant differences were observed between the intervention groups.

Overall, the study highlights the significant metabolic benefits of TRE with or without LCD on heart and thyroid health in individuals with MetS.

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