Efficacy of a Mobile App-Based Intervention for Young Adults With Anxiety Disorders: A Randomized Clinical Trial

Efficacy of a Mobile App-Based Intervention for Young Adults With Anxiety Disorders: A Randomized Clinical Trial

ABSTRACT

Young adults often face undertreatment for anxiety disorders. Maya, a mobile cognitive behavioral therapy (CBT) intervention, was tested in a randomized clinical trial. The study aimed to assess the efficacy and engagement with the intervention, comparing the effects of 3 incentive conditions.

Participants received a 6-week program of the intervention and were randomized to one of three different text message-based incentive conditions (gain-framed, loss-framed, or gain-social support).

The primary outcome was the change in anxious symptoms from baseline to the end of treatment, as measured by the Hamilton Anxiety Rating Scale (HAM-A). The Anxiety Sensitivity Index and the Leibowitz Social Anxiety Scale scores were secondary measures.

The results showed a decrease in anxiety across conditions from baseline to the end of the intervention, with symptomatic improvement maintained at the week 12 follow-up. The study found that a CBT application incorporating a full suite of CBT skills and embedded user engagement features was efficacious in improving symptoms in young adults with anxiety disorders.

These findings suggest that digital interventions represent a promising step toward wider dissemination of high-quality, evidence-based interventions.

TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT05130281.

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