Comparison of established and preliminarily proposed ASAS MRI working group cut-offs for inflammatory MRI lesions in the sacroiliac joints in radiographic and non-radiographic axial spondyloarthritis

Comparison of MRI Cut-offs for Inflammatory Lesions in Axial Spondyloarthritis

Background

A study compared the established and newly proposed MRI cut-offs for inflammatory lesions in the sacroiliac joints in patients with axial spondyloarthritis. The new cut-offs were preliminarily proposed in 2021.

Methods

The study used MRI scans from 657 patients to categorize them as MRI-positive or MRI-negative based on the established and preliminary MRI cut-offs. Clinical outcomes were then evaluated over a 48-week period.

Results

Both established and preliminary MRI cut-offs showed similar results in clinical outcomes. However, a small group of patients had discordant results between the two sets of cut-offs.

Conclusion

The preliminary 2021 MRI cut-offs may enhance the specificity of the established MRI inflammatory lesion definition.

Trial Registration

NCT02505542

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