Prognostic Impact of Admission Time in Infarct-Related Cardiogenic Shock
Study Overview
This study looks at how the timing of hospital admission affects patients with acute myocardial infarction complicated by cardiogenic shock (AMI-CS) and the effectiveness of extracorporeal life support (ECLS).
Key Objectives
The goal was to compare outcomes for patients admitted during regular hours (on-hours) versus those admitted during off-hours, and to assess how ECLS impacts these outcomes based on admission timing.
Study Methods
Patients with AMI-CS from the ECLS-SHOCK trial (2019-2022) were analyzed. We compared the 30-day mortality rates between on-hours and off-hours admissions using various statistical methods.
Results Summary
- Out of 417 patients, 48.4% were admitted during off-hours.
- Off-hours patients were generally younger and more likely to receive femoral access for coronary angiography.
- There was no significant difference in 30-day mortality between off-hours (46.0%) and on-hours (50.7%) admissions.
- ECLS did not significantly affect mortality rates for either group.
- However, ECLS was linked to a higher risk of bleeding, especially for on-hours admissions.
Conclusions
The timing of admission does not significantly impact the prognosis for AMI-CS patients, and ECLS shows similar effects regardless of when patients are admitted.
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